All endgame boss Unique loot tables in Diablo 4 Season 5

❘ Updated: 2024-08-08T13:38:35

Blizzard

Most of the Uniques and Mythics that you will come across in Diablo 4 Season 5 are a part of the endgame boss loot tables.

The game currently features six endgame bosses, all of which you’ve faced either in the main campaign or during the previous seasonal storylines.

While all six drop Uniques, only two of them drop the Mythics that are available in the game. So here are the loot tables for every endgame boss that you can farm in Diablo 4 Season 5.

All Diablo 4 endgame boss loot tables

Echo of Varshan

Class	Unique
Barbarian	Ring of Red Furor, Fields of Crimson, 100,000 Steps, Gohr’s Devastating Grips
Druid	Airidah’s Inexorable Will, Mad Wolf’s Glee, Vasily’s Prayer, Greatstaff of the Crone
Necromancer	Ring of the Sacrilegious Soul, Bloodless Scream, Deathless Visage, Deathspeaker’s Pendant
Rogue	Writhing Band of Trickery, Condemnation, Eyes in the Dark, Skyhunter
Sorcerer	Tal Rasha’s Iridescent Loop, Staff of Endless Rage, Esu’s Heirloom, Raiment of the Infinite
Universal	Frostburn, Mother’s Embrace

Element type: Shadow/Physical

How to summon: Collect different Malignant body parts (Gurgling Head, Trembling Hand, Malignant Heart, Blackened Femur.)

You can collect the parts above from the Tree of Wishpers caches. Once you’ve collected all the items, head into the Malignant Burrow below the Tree of Whispers to summon this boss.

The Echo of Varshan is a formidable foe.

Grigoire, the Galvanic Saint

Class	Unique
Barbarian	Ramaladni’s Magnum Opus, Rage of Harrogath, Battle Trance, The Butcher’s Cleaver, Twin Strikes
Druid	Insatiable Fury, Hunter’s Zenith, Waxing Gibbous, The Butcher’s Cleaver, Earthbreaker
Necromancer	Blood Artisan’s Cuirass, Howl from Below, Greaves of the Empty Tomb, Ebonpiercer
Rogue	Word of Hakan, Grasp of Shadow, Windforce, Saboteur’s Signet
Sorcerer	Staff of Lam Esen, Iceheart Brais, Gloves of the Illuminator, Flameweaver
Universal	Penitent Greaves

Damage type: Lightning

How to summon: Collect Living Steel from Helltides

Once you’ve collected enough Living Steel, make your way to the Hall of the Pentinent dungeon in Dry Steppes. You’ll need two Living Steel to summon him in World Tier 3, and five Living Steel to summon him in World Tier 4 in Diablo 4.

Grigoire, the Galvanic Saint can drop certain Uniques like the Hunter’s Zenith.

Lord Zir

Class	Unique
Barbarian	Ramaladni’s Magnus Opus, Rage of Harrogath, Gohr’s Devastating Grips, Overkill, The Butcher’s Cleaver
Druid	Mad Wolf’s Glee, Vasily’s Prayer, Greatstaff of the Crone, Fleshrender, The Butcher’s Cleaver
Necromancer	Blood Artisan’s Cuirass, Deathless Visage, Greaves of the Empty Tomb, Lidless Wall
Rogue	Grasp of Shadow, Eyes in the Dark, Skyhunter, Asheara’s Khanjar
Sorcerer	Staff of Endless Rage, Iceheart Brais, Raiment of the Infinite, Esadora’s Overflowing Cameo
Universal	Penitent Greaves, Razorplate, Temerity

Damage type: Fire

How to summon: Collect Exquisite Blood from Legion Events.

Although he was the boss in the past Season of Blood, you will still be able to summon him in the game. Head to The Ancient Seat in Fractured Peaks to summon Zir.

Lord Zir is one of the most difficult bosses in Diablo 4.

The Beast in Ice

Class	Unique
Barbarian	Fields of Crimson, 100,000 Steps, Ancients’ Oath, Battle Trance, Hellhammer, Ring of the Ravenous
Druid	Insatiable Fury, Hunter’s Zenith, Waxing Gibbous, Storm’s Companion, Unsung Ascetic’s Wraps
Necromancer	‍Bloodless Scream, Howl from Below, Deathspeaker’s Pendant, Ring of Mendeln, Mutilator Plate
Rogue	‍Condemnation, Word of Hakan, Windforce, Eaglehorn, Beastfall Boots
Sorcerer	Staff of Lam Esen, Esu’s Heirloom, Gloves of the Illuminator, The Oculus, Starfall Coronet
Universal	Frostburn, Mother’s Embrace, Fists of Fate, Tassets of Dawning Sky, Paingorger’s Gauntlets

Damage type: Cold

How to summon: Collect Distilled Fear by completing Tier 30+ Nightmare Dungeons.

Once you’ve collected enough Distilled Fear, make your way to the Occultist in Diablo 4 to craft the Glacial Fissure Nightmare Sigil. You can then use this sigil like you would with other Nightmare Sigils.

Beast in Ice is an extremely formidable enemy in the game.

Duriel, King of Maggots

Class	Unique
Barbarian	Tuskhelm of Joritz the Mighty
Druid	Tempest Roar, Dolmen Stone
Necromancer	Black River, Blood Moon Breeches
Rogue	Cowl of the Nameless, Scoundrel’s Leathers
Sorcerer	‍Flamescar, Blue Rose
Universal	Godslayer Crown, Flickerstep, Tibault’s Will, X’Fal’s Corroded Signet, Soulbrand, Banished Lord’s Talisman
Mythics	Doombringer (Barb, Necro, Rogue)‍, The Grandfather (Barb, Necro), Melted Heart of Selig, Andariel’s Visage‍, Harlequin Crest‍, Tyrael’s Might, ‍Ring of Starless Skies, Ahavarion Spear of Lycander (Druid, Sorc)

Damage type: Poison

How to summon: Collect Mucus-Slick Eggs and Shards of Agony by defeating Varshan and Grigoire, respectively.

It’s worth remembering that the Mucus-Slick Eggs are only available in World Tier 4. So once you’ve collected the two items, you need to make your way to the Gaping Crevasse dungeon and find the altar to summon Duriel, who happens to be one of the two bosses to drop Mythic gear.

You can get Tibault’s Will by defeating Duriel.

Echo of Andariel, Maiden of Anguish

Class	Unique
Barbarian	Tuskhelm of Joritz the Mighty
Druid	Tempest Roar, Dolmen Stone
Necromancer	Black River, Blood Moon Breeches
Rogue	Cowl of the Nameless, Scoundrel’s Leathers
Sorcerer	‍Flamescar, Blue Rose
Universal	Godslayer Crown, Flickerstep‍, Tibault’s Will, X’Fal’s Corroded Signet, Soulbrand, Banished Lord’s Talisman, Azurewrath
Mythics	Doombringer (Barb, Necro, Rogue)‍, The Grandfather (Barb, Necro), Melted Heart of Selig, Andariel’s Visage‍, Harlequin Crest‍, Tyrael’s Might, ‍Ring of Starless Skies, Ahavarion Spear of Lycander (Druid, Sorc)

Damage type: Fire/Poison

How to summon: Collect Sandscorched Shackles in Diablo 4 Season 4 from Lord Zir, and Pincushioned Dolls from The Beast in Ice to summon her.

Needlessly to say, you’ll have to be in World Tier 4 to summon her, and the jump in difficulty compared to her base version in the campaign is massive. Once you have these items, make your way to Hanged Man’s Hall to summon her.

Other than Duriel, Andariel is the only other endgame boss who drops Mythic gear in Diablo 4.

Andariel the Maiden of Anguish in Diablo 4

You’ll need to take on two Uber bosses before fighting Andariel.

Apart from these, the game features other Uniques too, which are a part of the Infernal Hordes loot table, a brand new rogue-like mode introduced in Diablo 4 Season 5.